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| Attribute | Sumatriptan | Ibuprofen |
|---|---|---|
| Simple | Migraine-specific medicine. | Pain relief medicine. |
| Drug class | Serotonin (5-HT1) receptor agonist. | NSAID (Non-Steroidal Anti-Inflammatory Drug). |
| Prescription | Rx only | OTC |
| Uses | Migraine, Cluster headache | Headache, Fever, Tooth pain, Period pain, Muscle pain, Arthritis |
| Forms | Tablet, Nasal spray, Injection | Tablet, Capsule, Syrup, Gel, Injection |
| Adult dosage | 50–100 mg at start of migraine; may repeat once after 2 hours. | 200–400 mg every 4–6 hours as needed (max 1200 mg/day OTC). |
| Pregnancy | Ask your doctor | Avoid in 3rd trimester |
| Common side effects | Tingling, Chest tightness, Drowsiness | Heartburn, Dizziness, Headache |