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| Attribute | Sumatriptan | Aspirin |
|---|---|---|
| Simple | Migraine-specific medicine. | Painkiller and blood thinner. |
| Drug class | Serotonin (5-HT1) receptor agonist. | NSAID and antiplatelet agent (acetylsalicylic acid). |
| Prescription | Rx only | OTC |
| Uses | Migraine, Cluster headache | Pain, Fever, Heart attack prevention, Stroke prevention |
| Forms | Tablet, Nasal spray, Injection | Tablet, Chewable tablet, Enteric-coated tablet |
| Adult dosage | 50–100 mg at start of migraine; may repeat once after 2 hours. | 300–600 mg every 4–6 hours for pain; 75–100 mg daily for heart protection. |
| Pregnancy | Ask your doctor | Avoid in 3rd trimester |
| Common side effects | Tingling, Chest tightness, Drowsiness | Stomach upset, Heartburn |